Week 16 of the 2024 NFL schedule is loaded with pivotal matchups that could have playoff implications, including Steelers vs. Ravens (-6.5, 45), Eagles vs. Commanders (+3.5, 45.5), Vikings vs. Seahawks (+4, 42.5) and 49ers vs. Dolphins (-1.5, 46). The Week 16 NFL schedule wraps up on Monday Night Football with Saints vs. Packers (-13.5, 42), giving you plenty of options for NFL confidence pool picks and NFL office pool picks.

Before making any Week 16 NFL office pool picks, you NEED to see which teams the SportsLine Projection Model is backing in its NFL football pool picks.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 16 of the 2024 NFL season on an incredible 27-11 hot streak on top-rated NFL picks this year. Longer term, it is on a 207-139 roll on top-rated NFL picks that dates back to the 2017 season and a 61-32 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone following has seen HUGE returns!

In Week 16, we can tell you the model is high on the Indianapolis Colts (-4.5, 42.5) beating the Tennessee Titans, 25-20. Both teams have struggled in recent weeks, but this is the perfect bounce-back spot for the home team. The Colts have won three straight against the Titans in this AFC South rivalry, most recently securing a 20-17 victory on the road in October. The Titans are 1-9 against the spread in their last 10 games, while the Colts are 9-1 in their past 10 games when playing as the favorite. 

The model has also locked in NFL picks for every Week 16 NFL game! You ABSOLUTELY need to see which teams the model is backing before locking in your NFL pool picks!

So which teams win outright in Week 16? ... Join SportsLine right now to see the SportsLine Projection Model's Week 16 NFL office pool picks, all from the model that has returned well over $7,000 on its top-rated NFL picks!