A star-studded NFC showdown is set to take place when the San Francisco 49ers host the Dallas Cowboys on Sunday Night Football. There will be no shortage of big names to utilize as NFL DFS picks with the likes of Dak Prescott, CeeDee Lamb, George Kittle and Deebo Samuel. But an effective NFL DFS strategy should also incorporate more cost-effective options for 49ers vs. Cowboys. Before locking in your NFL DFS picks on sites like DraftKings and FanDuel for Cowboys vs. 49ers, you NEED to see what Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings.

He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once! Now, McClure has turned his attention to 49ers vs. Cowboys on Sunday Night Football and locked in his top daily Fantasy football picks. 

We can tell you one of McClure's top NFL DFS picks for Sunday Night Football is 49ers running back Christian McCaffrey. Part of McClure's optimal NFL DFS strategy also includes rostering Cowboys running back Tony Pollard. Despite not finding the endzone since scoring twice in Week 1, Pollard has racked up the yardage over recent games. He's averaged 96.7 scrimmage yards over the last three weeks even after not playing in the fourth quarter of last week's blowout of New England.

McClure is also targeting a player who could go off for MASSIVE numbers in Cowboys vs. 49ers on Sunday Night Football! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NFL DFS picks 49ers vs. Cowboys, and which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!