The 2023 Week 7 NFL schedule comes to a close with Monday Night Football between the San Francisco 49ers and Minnesota Vikings. Kickoff is at 8:15 p.m. ET at U.S. Bank Stadium. The MNF NFL DFS player pool features a mix of high-end, proven fantasy options, and young, high upside options, meaning there will be tough decisions to be made when building NFL DFS lineups. Should perennial Pro Bowl candidates like Kirk Cousins, T.J. Hockenson, Brock Purdy, or George Kittle be part of your Monday Night Football DFS lineups or NFL DFS stacks? San Francisco wide receiver Deebo Samuel (shoulder) and Vikings wide receiver Justin Jefferson (hamstring, IR) are both out. All-Pro running back Christian McCaffrey (oblique) has been cleared to play and will be the highest-priced option in the MNF player pool.

Before locking in any playoff NFL DFS lineups or NFL DFS stacks for 49ers vs. Vikings on Monday Night Football on sites like DraftKings and FanDuel, you NEED to see what SportsLine's Jimmie Kaylor has to say.

Kaylor is a NFL and DFS expert for SportsLine, who opened the 2022 NFL season by winning DraftKings' NFL Showdown Thursday Kickoff Millionaire contest. He edged out over 355,000 other entrants in the contest and also has multiple five-figure tournament wins on his DFS resume. Kaylor, who cashed big all season in 2022, has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America, and his background as a former college and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks.  

Kaylor hit on epic NFL DFS picks all season in 2022. He was all over Travis Kelce's four-touchdown performance against the Raiders on Monday Night Football, Kirk Cousins' 460-yard, four-TD performance on Thanksgiving Day, and T.J. Hockenson's 13 catches for 109 yards and two touchdowns in Week 15.

This year, Kaylor has been all over players like Justin Jefferson (11-159), D'Andre Swift (175-1), DeVonta Smith (4-132-1), T.J. Hockenson (7-66-2), D.J. Moore (8-230-3), David Montgomery (121-3), Ja'Marr Chase (12-141), and Alvin Kamara (12-91, 76) in single-game slates. Anyone who followed his picks cashed in BIG!

Now, Kaylor has turned his attention to Vikings vs. 49ers on Monday Night Football in Week 7 and locked in his top daily Fantasy football picks.

We can tell you that one of Kaylor's top NFL DFS picks for Monday Night Football is 49ers wide receiver Brandon Aiyuk. Part of Kaylor's optimal NFL DFS strategy also includes rostering Minnesota tight end T.J. Hockenson. "With Justin Jefferson still sidelined, Hockenson is Kirk Cousins' top target in the Minnesota offense. I expect the 49ers to get up early, forcing Minnesota to throw the ball more often than planned. San Francisco is elite defensively, but I expect the volume to be there for Hockenson to have a productive fantasy night on MNF," Kaylor told SportsLine.

Kaylor is also targeting another under-the-radar player for MNF who could post HUGE numbers and carry your lineups to victory! His NFL DFS picks could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups!

Be sure to follow Jimmie (@jimmiekaylor) on Twitter for notifications about rosters changes/updates

What are the top NFL DFS picks for the MNF matchup of 49ers vs. Vikings on FanDuel and DraftKings? And which player is a MUST-ROSTER? ... Join SportsLine now to see NFL expert and DraftKings Millionaire winner Jimmie Kaylor's top picks, stacks, and player pools for FanDuel and DraftKings, all from a DFS expert who won a prestigious Millionaire Maker tournament!