Many of the NFL's biggest stars had standout games last week. Justin Herbert had 340 passing yards, while Derrick Henry and Justin Jefferson went over 100 yards rushing and receiving, respectively. They all could be popular NFL DFS picks for Week 5's Sunday slate. Before you set your Week 5 NFL DFS lineups, you NEED to hear what SportsLine daily Fantasy expert Mike McClure has to say.

McClure is a legendary professional DFS player with over $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of Millionaire Maker tournament wins in 2022 on DraftKings. His lineups also finished inside the top one percent in more than a dozen other tournaments last season.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.

In Week 4, McClure had Lions running back Jamaal Williams as one of his core NFL DFS picks for both FanDuel and DraftKings: The result: Williams had 108 rushing yards and two touchdowns, returning 26.9 points on DraftKings and 23.4 points on FanDuel. Anybody who had him in their lineups was well on the way to a HUGE day.

We can tell you one of McClure's top NFL DFS picks for Week 5 is Rams receiver Cooper Kupp at $9,600 on DraftKings and $9,500 on FanDuel. Part of McClure's optimal NFL DFS strategy includes rostering Buccaneers running back Leonard Fournette at $6,900 on DraftKings and $7,800 on FanDuel. Tampa all but ignored the run in last week's loss, but Fournette made an impact through the air with 57 yards and a touchdown. He is the focal point of the Bucs' offense, ranking ninth in the NFL in touches and averaging 83.8 scrimmage yards per game.

McClure is also targeting a player who could go off for MASSIVE numbers in Week 5! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who they are before locking in any lineups.

What are the top NFL DFS picks for Week 5? And which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NFL DFS!