It's a matchup of NFC South contenders when Tom Brady and the Tampa Bay Buccaneers visit Drew Brees and the New Orleans Saints on Sunday. Kickoff is set for 4:25 p.m. ET at the Mercedes-Benz Superdome. The Saints are a 3.5-point favorite in the latest Bucs vs. Saints odds at William Hill, while the over-under is 47.5. Before making any Bucs vs. Saints picks of your own, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up over $7,000 for $100 players on its top-rated NFL picks since its inception five years ago. It also enters the 2020 NFL season on an incredible 96-65 roll on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is WAY UP.

Now, it has analyzed Bucs vs. Saints, and we can tell you it's leaning Over. It has also generated a STRONG against the spread pick that cashes in well over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any NFL picks of your own.

So who wins Bucs vs. Saints? And which side of the spread can you bank on in well over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Bucs vs. Saints spread you should be all over on Sunday, all from the advanced model on a 96-65 roll on top-rated NFL picks!