Before setting your NBA DFS lineups on sites like DraftKings and FanDuel for Wednesday, December 21, you NEED to see what Mike McClure has to say. 

McClure is a DFS professional with over $2 million in career winnings. He's also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account.

This allows him to find the best NBA DFS values and create optimal lineups that he shares only over at SportsLine. They're a must-see for any NBA DFS player.

On Tuesday, he highlighted Suns center Deandre Ayton as one of his NBA DFS picks in DraftKings and FanDuel player pools. The result: Ayton finished with 30 points, 13 rebounds and a block to return 47.75 points on DraftKings and 44.6 points on FanDuel. Anybody that included him in their lineups was well on the way to a profitable day.

For Wednesday, one of McClure's top NBA DFS picks is Lakers forward LeBron James, who is listed at $9,900 on DraftKings and $11,100 on FanDuel. Another part of McClure's optimal NBA DFS strategy includes rostering Warriors center James Wiseman ($3,000 on DraftKings and $3,700 on FanDuel). Wiseman is listed as questionable (thumb), but logged a season-high 22 minutes in his last game on Tuesday against the Knicks and scored four points to go with three rebounds, two blocks and a steal. The Warriors' offense doesn't typically showcase its frontcourt, but with so many everyday players out on Wednesday, somebody needs to step up.

McClure is also targeting a player who could go off for MASSIVE numbers on Wednesday! This pick could be the difference between winning your tournaments and cash games or going home with nothing! You ABSOLUTELY need to see who it is before locking in any lineups.

What are the top NBA DFS picks for Wednesday? And which player is a MUST-ROSTER? ... Join SportsLine now to see DFS pro Mike McClure's top picks, stacks, and player pools for FanDuel and DraftKings, and cash in BIG on NBA DFS!