Two division leaders in the American League collide on Tuesday when the Baltimore Orioles square off against the Seattle Mariners in MLB's game of the day at T-Mobile Park in Seattle. The Orioles (53-31) lead the AL East by percentage points over the Yankees (54-32). Meanwhile the Mariners (47-39) lead the AL West by three games over the Astros (43-41). Tuesday's first pitch is set for 9:40 p.m. ET.

The Orioles are -116 favorites in the latest Orioles vs. Mariners odds, while the Mariners are -104 underdogs. The over/under for total runs scored is 7. The game is one of 15 on the MLB schedule for Tuesday. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 15 of the 2024 MLB season a profitable 44-34 on all-top rated MLB picks this season. Dating back to last season, it is on a 22-8 roll on top-rated run-line picks (+935). Anybody following has seen strong returns.

Now, the model has set its sights on the MLB schedule for Tuesday and has generated a three-leg parlay that would pay more than 6-1! The parlay doesn't start until 7:40 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the Twins (-110) to beat the Tigers. But the model has two other picks, including a play on an underdog that wins outright well over 50% of the time! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which AL underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of more than 6-1? ... Join SportsLine right now to find out which picks you should be all over on Tuesday, all from the model that is 44-34 on all top-rated MLB picks this season.