The Houston Astros attempt to continue their surge when they visit the Toronto Blue Jays on Wednesday for the third contest of their four-game series. The teams split the first two games of the set, but Houston (43-42) has won 10 of its last 12 games to get over the .500 mark for the first time this season. The run has helped the Astros climb within three games of Seattle for first place in the American League West. Wednesday's first pitch is set for 7:07 p.m. ET.

Houston is a -114 favorite in the latest Astros vs. Blue Jays odds, while Toronto is a -105 underdog. The over/under for total runs scored is 8.5. The game is one of 15 on the MLB schedule for Wednesday. (See up-to-date lines for every game on our MLB odds page.)

Before making any MLB picks or parlays, be sure to see the predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 15 of the 2024 MLB season a profitable 44-34 on all-top rated MLB picks this season. Dating back to last season, it is on a 22-8 roll on top-rated run-line picks (+935). Anybody following has seen strong returns.

Now, the model has set its sights on the MLB schedule for Wednesday and has generated a three-leg parlay that would pay almost 9-1! The parlay doesn't start until 7:20 p.m. ET, giving you plenty of time to make your MLB picks.

We can tell you that one of the picks is the San Diego Padres (+122) to beat the Texas Rangers. But the model has two other picks, including a play on a big AL underdog! You ABSOLUTELY need to see them before locking in any MLB picks of your own.

So which AL underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of almost 9-1? ... Join SportsLine right now to find out which picks you should be all over on Wednesday, all from the model that is 44-34 on all top-rated MLB picks this season.