Baseball fans could be seeing a preview of the National League Championship Series when the San Francisco Giants and Milwaukee Brewers open a three-game series on Friday at American Family Field in Milwaukee. First pitch on Friday is 8:10 p.m. ET. The Brewers are -157 money-line favorites in the latest Brewers vs. Giants odds from Caesars Sportsbook, while the Giants are +147 underdogs.

The game is one of 15 on Friday's loaded MLB schedule. (See up-to-date lines for every game on our MLB odds page.)

Before entering any MLB picks or parlays, you NEED to see the latest predictions from the SportsLine Projection Model. 

This model, which simulates every pitch of every game 10,000 times, is a profitable 140-113 on top-rated MLB money-line picks through 18 weeks in the 2021 season. It also had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line picks. Anyone following it has seen some huge returns.

Now, the model has set its sights on the MLB schedule for Friday. Using its top picks for the day, the model has generated a four-leg parlay that would pay well over 23-1! The best part is that the parlay doesn't start until 7:05 p.m. ET, giving you plenty of time to make your MLB picks!

We can tell you that one of the picks is the Tigers (+143) to beat the Indians (7:10 p.m. ET). But the model has three other picks, including an even bigger underdog pulling off a big upset! You ABSOLUTELY need to see it before locking in any MLB picks of your own.

So which underdog is a MUST-BACK? And what other teams do you need to include in your parlay for a payout of well over 23-1? ... Join SportsLine right now to find out which picks you should be all over on Friday, all from the model that is off to a fast start in 2021!