Loyola Chicago's tenure in the AP Top 25 was shot-lived after the Ramblers lost to Missouri State on January 22 in their first game after making their debut in the rankings. The two sides play each other again in a Missouri Valley Conference matchup at 2 p.m. ET on Sunday at JQH Arena. Bears forward Isiaih Mosley had his best performance of the season in their last meeting, with 40 points and eight rebounds in the Missouri State victory. Both programs have eight conference wins, but with a game in-hand, Loyola currently sits atop the Missouri Valley Conference standings.

The Ramblers are favored by two points in the latest Missouri State vs. Loyola Chicago odds from Caesars Sportsbook, and the over-under is set at 134.5. Before you make any Loyola Chicago vs. Missouri State picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Missouri State vs. Loyola Chicago 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely need to see it before locking in your own picks.

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