A key Southeastern Conference matchup has the Mississippi State Bulldogs (12-4, 1-2 SEC) going on the road to play the No. 8 Kentucky Wildcats (12-3, 2-1 SEC) on Wednesday at 7 p.m. ET as coach John Calipari goes for win No. 400 as Kentucky coach. The Wildcats are 6.5-point favorites in the latest Mississippi State vs. Kentucky odds via SportsLine consensus, while the over/under for total points scored is 155 (see up-to-date odds for every game this week on our college basketball odds page). 

Before making any Mississippi State vs. Kentucky picks, you need to check out the college basketball predictions from the SportsLine Projection Model.

The model simulates every Division I college basketball game 10,000 times. It enters Week 11 of the 2023-24 season on a 110-73 roll on all top-rated college basketball picks dating back to last season, returning more than $2,000 for $100 players. It is also off to a sizzling 15-5 start on top-rated spread picks this season. Anyone following has seen HUGE returns!

The model knows Kentucky senior guard Antonio Reeves has been red hot of late, scoring 20 or more points in three of his last five games, including a 30-point performance in a 95-76 win at Louisville on Dec. 21. He is coming off a 22-point and six-rebound effort in the loss to Texas A&M on Saturday. He was the 2023 SEC Sixth Man of the Year. This season, he is averaging a team-high 18.9 points per game, along with 4.4 rebounds and 1.4 assists.

The model also knows Bulldogs senior forward Tolu Smith has been a welcome addition after returning from a foot injury he sustained in the preseason. In his four games since coming back, he is averaging 16.8 points, 6.8 rebounds and one assist in 24.3 minutes of action. The fifth-year player has averaged in double figures all four of his years at Mississippi State after beginning his collegiate career at Western Kentucky.

Now, the model has set its sights on Mississippi State vs. Kentucky. We can tell you the model is leaning Under on the point total, and it also says one side of the spread hits nearly 70% of the time! You ABSOLUTELY need to see the model before locking in any college basketball picks.

Who wins Mississippi State vs. Kentucky, and which side of the spread hits nearly 70% of the time? ... Join SportsLine right now to find out which side of the spread you should be all over, all from that's on a 110-73 roll on top-rated college basketball picks!