Mississippi State hosts a Pac-12 opponent in Week 2 as the Arizona Wildcats head to Starkville to take on the Bulldogs on Saturday night. Kickoff is set for 7:30 p.m. ET from Davis Wade Stadium. Both teams defeated FCS opponents in Week 1 and head into this matchup with a record of 1-0. Last year, the Bulldogs pulled away from the Wildcats in the second half, defeating Arizona 39-17 in Tucson. Mississippi State is a 9-point favorite, while the over/under is set at 60 (see up-to-date odds for every game this week on our college football odds page) in the latest Arizona vs. Mississippi State odds.

Before making any Mississippi State vs. Arizona picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. The proprietary computer model is off to a fast 4-2 start on all-top rated college football picks this season. Since its inception, it has generated a stunning profit of more than $2,500 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows that the Wildcats are improved under third-year head coach Jedd Fisch, having walloped FCS Northern Arizona, 38-3 in Week 1. Arizona features a balanced attack led by QB Jayden de Laura, who threw for 285 yards and three touchdowns and ran for 47 yards and a score against the Lumberjacks. In addition to four stable running backs, the Wildcats boast a loaded group of receivers including Jacob Cowing (3-38-1 vs. NAU), Tetairoa McMillian (3-65-1), and Colorado transfer Montana Lemonious-Craig (2-49-0).

The model also knows that the Bulldogs easily dispatched FCS SE Louisiana, 48-7 in Week 1 led by 127 yards rushing and two touchdowns from RB Jo'Quavious Marks. Quarterback Will Rogers threw for 227 yards and two scores and looks to repeat his 313 yard, four touchdown passing performance against the Wildcats last season. In that game, the Bulldogs' defense held Arizona to only 40 rushing yards, which forced the Wildcats to be one dimensional, especially in the second half.

Now, it has set its sights on Arizona vs. Mississippi State. We can tell you the model is leaning Over on the point total, and it also says one side of the spread hits in 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Mississippi State vs. Arizona, and which side of the spread hits in 60% of simulations? Join SportsLine right now to find out which side of the Arizona vs. Mississippi State spread you should be all over, all from the model that's up nearly $2,500 on top-rated CFB spread picks since its inception!