One of college football's most storied rivalries is on tap for Saturday when the No. 2 Ohio State Buckeyes and the No. 3 Michigan Wolverines square off in The Game. Kickoff is at noon ET at Michigan Stadium in Ann Arbor. The Buckeyes are coming off a 37-3 blowout win over Minnesota, while the Wolverines notched a hard-fought 31-24 win over Maryland. Michigan head coach Jim Harbaugh will be serving the final game of his suspension on Saturday. The Wolverines have won the last two matchups in this rivalry and lead the all-time series 60–51–6.

The Wolverines are 3-point favorites in the latest Ohio State vs. Michigan odds via SportsLine consensus, while the over/under for total points scored is 46. Michigan is a -153 (risk $153 to win $100) favorite on the money line, with Ohio State listed as a +128 underdog (see up-to-date odds for every game this week on our college football odds page). 

Before you make any Michigan vs. Ohio State picks or any other college football predictions, you NEED to see which side proven SportsLine expert Jimmie Kaylor is on. 

Kaylor is a NFL, college football, and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor has been red-hot all season, going 70-28-2 overall on his college football best bets for SportsLine this season so far. He is up over 43.05 units, returning a profit of $4,305 for $100 bettors. Anyone who has followed his picks this season is way up.

Kaylor knows that you can typically throw out the records when these bitter rivals meet. Michigan will again be without head coach Jim Harbaugh, who is serving the final game of his suspension. The Wolverines have gone 2-0 in his absence, but this game will be their toughest test of the season. Michigan is an experienced team that has been dominant on both sides of the ball in 2023.

Kaylor, however, also factored in that Ohio State is once again one of the deepest and most talented teams in the country. The Buckeyes have one of the program's best defenses in recent memory, and enter this matchup allowing only 9.3 points and 252.9 total yards per game. Ohio State also has arguably the best overall player in this game in wide receiver Marvin Harrison Jr.

Now, Kaylor has locked in a confident against-the-spread pick for Ohio State vs. Michigan. We can tell you he's leaning Under on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Michigan vs. Ohio State in the The Game on Saturday, and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the spread to jump on, all from the expert who is on a 69-28 roll betting on college football this season, and find out!