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    Michigan vs. Ohio State prediction, odds, line: Advanced college football model reveals picks for Saturday's Big Ten Conference East Division showdown

    SportsLine's projection model has generated Week 13 CFB picks for the Big Ten East matchup between the No. 3 Michigan Wolverines and No. 2 Ohio State Buckeyes

    The second-ranked Ohio State Buckeyes are seeking a sixth Big Ten Conference Championship Game appearance when they take on the defending Big Ten East Division champion and No. 3 Michigan Wolverines on Saturday. The Buckeyes (11-0, 8-0) have not lost a Big Ten game at Ohio Stadium since the 2015 season, and have won 29 consecutive conference home games. The Wolverines (11-0, 8-0), who look to snap a nine-game losing streak in Columbus, last won at Ohio Stadium in 2000, a 38-26 triumph to capture the conference championship.

    The game from Ohio Stadium in Columbus, Ohio, kicks off at noon ET. Ohio State is an 8-point favorite in the latest Michigan vs. Ohio State odds from Caesars Sportsbook, while the over/under for total points scored is 56. (See up-to-date odds for every game this week on our college football odds page.) 

    Before you make any Michigan vs. Ohio State picks or college football predictions, you NEED to see the predictions from the SportsLine Projection Model.

    The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen HUGE returns!

    The model knows the Buckeyes are led by junior quarterback C.J. Stroud. He has completed 204 of 307 passes (66.4%) for 2,991 yards and 35 touchdowns. He has been picked off just four times and has a rating of 183.3. He has thrown for over 300 yards four times and has passed for four or more touchdowns in six games. His best game was a 21 of 26 performance (80.8%) for 361 yards and six touchdowns in a 49-20 win at Michigan State.

    The model also knows the Wolverines are led by sophomore quarterback J.J. McCarthy, who has been dominant this season, completing 165 of 247 passes (66.8%) for 1,952 yards and 14 touchdowns with just two interceptions for a rating of 150.3. He has also rushed 49 times for 213 yards (4.3 average) and three touchdowns. His best game was a 28 of 36 performance (77.8%) for 304 yards and three touchdowns and one interception in a 31-10 win at Indiana on Oct. 8.

    Now, the model has set its sights on Michigan vs. Ohio State. We can tell you it is leaning Over the total, and it also says one side of the spread hits well over 50% of the time! You ABSOLUTELY need to see it before locking in any college football picks.

    Who wins Michigan vs. Ohio State? And which side of the spread hits well over 50% of the time? ... Join SportsLine right now to find out which side of the Michigan vs. Ohio State spread you should be all over Saturday, all from the model on a roll on college football picks!

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    SportsLine Staff
    SportsLine Staff

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