A Big Ten battle is on tap between the Michigan State Spartans and the No. 3 Ohio State Buckeyes at 4 p.m. ET on Saturday at Spartan Stadium. Ohio State has won all five of its games by double digits, including a 49-10 blowout against Rutgers last week. The Buckeyes are favored by 27 points in the latest Michigan State vs. Ohio State odds from Caesars Sportsbook, while the over/under is set at 65. 

Before you make any Ohio State vs. Michigan State picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of more than $3,100 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Michigan State vs. Ohio State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Michigan State vs. Ohio State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!