The Maryland Terrapins will take on the SMU Mustangs at 7:30 p.m. ET on Saturday at Maryland Stadium. The Terrapins are 2-0 overall and 1-0 at home, while SMU is 2-0 overall and 1-0 on the road. Maryland ended last year fifth in the Big Ten's East Division, while the Mustangs ended up sixth in the American Athletic. 

The Terrapins are favored by 2.5 points in the latest Maryland vs. SMU odds from Caesars Sportsbook, and the over/under is set at 72.5. Before making any SMU vs. Maryland picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It enters Week 3 of the 2022 college football season on a 50-41 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

Now, it has simulated Maryland vs. SMU 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. You absolutely need to see it before locking in your own picks.

So who wins Maryland vs. SMU? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.