The No. 9 Louisville Cardinals can clinch their first appearance in the ACC Championship Game when they face the Miami Hurricanes on Saturday in a conference clash at Hard Rock Stadium outside of Miami. The Cardinals (9-1 overall, 6-1 in ACC) sit in second place in the conference, behind only No. 4 Florida State (10-0, 8-0), which already has clinched a spot in the ACC title game. Louisville needs a win over the Hurricanes (6-4, 2-4) to nail down its spot in the game on Dec. 2 in Charlotte.

Kickoff is scheduled for noon ET. The Hurricanes are -1 in the latest SportsLine consensus Louisville vs. Miami odds. The over/under for total points scored is 46.5. (see up-to-date odds for every game this week on our college football odds page.)

Before you make any Miami vs. Louisville picks, you need to see the college football predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Since its inception, it has generated a strong profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

The model knows that the Cardinals have one of the best defenses in program history. Louisville leads the conference and ranks 12th in the country in scoring defense (17.1 points per game). The team also ranks 16th in the nation in total defense (300.1 yards per game). With a strong close to the season, this year's Cardinals could become the first Louisville defense to finish the season allowing fewer than 300 yards a game since 2013.

The model also knows that the Hurricanes defense has excelled this season at stopping the run. Led by defensive coordinator Lance Guidry, a candidate for the Broyles Award, Miami is allowing just 86.0 rushing yards per game, which leads the ACC and ranks sixth in the nation. Last week the Hurricanes held No. 4 Florida State to just 57 rushing yards.

Now, the model has set its sights on Louisville vs. Miami. We can tell you it is leaning Over the total, and it also says one side of the spread hits in well over 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Miami vs. Louisville? And which side of the spread hits in well over 60% of simulations? ... Join SportsLine right now to find out which side of the Louisville vs. Miami spread you should be all over Saturday, all from the model on a roll on college football picks!