The No. 3 Iowa Hawkeyes look to win their third straight game against the cross-state rival Iowa State Cyclones in a key non-conference matchup on Friday. Tip-off from Carver-Hawkeye Arena in Iowa City, Iowa, is set for 9 p.m. ET. Iowa is favored by 12.5-points at William Hill Sportsbook, while the Over-Under is set at 158.5 (see up-to-date odds for every game this week on our college basketball lines page). Before making any Iowa State vs. Iowa picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past four-plus years, the proprietary computer model has generated an impressive profit of almost $2,700 for $100 players on its top-rated college basketball picks against the spread. It's also off to a fast start in the 2020-21 season, going 5-1 on all its top-rated picks and returning over $400. Anyone who has followed it has seen HUGE returns.

Now, it has set its sights on Iowa State vs. Iowa. We can tell you the model is leaning over the total, and it also says one side of the spread hits in over 50 percent of simulations! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Iowa State vs. Iowa? And which side of the spread hits in over 50 percent of simulations? ... Join SportsLine right now to find out which side of the Iowa State vs. Iowa spread you should be all over Friday, all from the model on a roll on college basketball picks!