The Houston Cougars go on the road to face Tulane Green Wave on Thursday night in AAC play. The Cougars (4-1) have won four games in a row, with their last win coming against Tulsa 45-10. Tulane (1-4) has struggled to find a rhythm, dropping three games in a row. The Cougars are favored by 6.5 points in the latest Houston vs. Tulane odds from Caesars Sportsbook, while the Over-Under is set at 60 points. Kickoff from Yulman Stadium is set for 7:30 p.m. ET. 

Before making any Houston vs. Tulane picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,400 for $100 players on its top-rated college football picks against the spread. It also enters Week 6 of the 2021 season on a 12-4 run on all top-rated college football side picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Houston vs. Tulane 10,000 times and the results are in. We can tell you that the model is leaning Over the total, and it's also generated a point-spread pick that hits in over 60 percent of simulations. You absolutely need to see it before locking in your own picks. 

So who wins Houston vs. Tulane? And which side of the spread hits in over 60 percent of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.