We've got an exciting Eastern Conference matchup on Wednesday's NBA schedule as the Charlotte Hornets and Detroit Pistons are set to tip at 7 p.m. ET at the Spectrum Center. Charlotte is 2-5 overall and 1-3 at home, while Detroit is 3-5 overall and 2-2 on the road. The Hornets are favored by 1.5 points in the latest Hornets vs. Pistons odds via SportsLine consensus, and the over/under is 222.5 points.

Before entering any Hornets vs. Pistons picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 3 of the 2024-25 NBA season on a sizzling 101-64 roll on all top-rated NBA picks dating back to last season, returning more than $3,000. Anyone following at sportsbooks and on betting apps has seen huge returns.

The model has simulated Hornets vs. Pistons 10,000 times and the results are in. We can tell you that the model is leaning Over the total, and it's also generated a point-spread pick that is hitting in almost 70% of simulations. 

So who wins Hornets vs. Pistons? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.