The Cleveland Guardians and Detroit Tigers wrap up a series between division rivals at 1:10 p.m. ET on Wednesday. Cleveland is listed as a -190 favorite (risk $190 to win $100) at Caesars Sportsbook, while the Over-Under is set at 8 (see up-to-date odds for every game this week on our MLB odds page). Before making any Guardians vs. Tigers picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 271-232 on top-rated MLB money-line picks since the start of the 2021 season, returning well over $500 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

The model knows the Guardians should benefit from Detroit's offensive shortcomings. The Tigers are very much struggling in run production, and Cleveland is projected to deploy an elite starting pitcher in Shane Bieber. The 2020 AL Cy Young winner has a 2.72 ERA over the last three seasons. In 2022, Bieber has a 3.16 ERA with only 2.2 walks allowed and 0.7 home runs allowed per nine innings.

The model also knows the Tigers have quality speed, with a top-five mark in the AL in triples. On the mound, Detroit can also rely on steadiness with veteran right-hander Michael Pineda. The 33-year-old former All-Star has a 3.62 ERA and a 1.13 WHIP this season. Pineda is also walking only 1.3 batters per nine innings, and he has a 2.82 ERA in home starts this season.

Now, it has set its sights on Guardians vs. Tigers. We can tell you the model is leaning Under the total, and it also says one team has all the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Who wins Guardians vs. Tigers? And which team has all the value on the money line? ... Join SportsLine right now to find out which side of the Guardians vs. Tigers matchup you should be all over Wednesday, all from the model on a roll on MLB picks!