We've got another exciting Western Conference matchup on the NBA schedule as the Memphis Grizzlies and Oklahoma City Thunder are set to tip at 9:30 p.m. ET on Wednesday at FedEx Forum. Memphis is 38-23 overall and 22-9 at home, while Oklahoma City is 50-11 overall and 23-7 on the road. The Thunder are favored by 8.5 points in the latest Grizzlies vs. Thunder odds, and the over/under is 250.5 points.

Before entering any Thunder vs. Grizzlies picks, you'll want to see the NBA predictions from the advanced computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in betting profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters Week 20 of the 2024-25 NBA season on a sizzling 147-107 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It's also an outstanding 18-10 (64%) on top-rated spread picks this season. Anyone following at sportsbooks and on betting apps could have seen huge returns.

The model has simulated Grizzlies vs. Thunder 10,000 times and the results are in. We can tell you that the model is leaning Under the total, and it's also generated a point-spread pick that is hitting in well over 50% of simulations. 

So who wins Grizzlies vs. Thunder? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks.