The Florida State Seminoles will take on the Penn Quakers at 9 p.m. ET on Wednesday at the Donald L. Tucker Center in Tallahassee. The Seminoles are favored by 19.5 points in the latest Florida State vs. Penn odds from Caesars Sportsbook, and the over-under is set at 145.5. Before you make any Penn vs. Florida State picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five years, the proprietary computer model has generated an impressive profit of $2,200 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has simulated Florida State vs. Penn 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick where one side has all the value. You absolutely need to see it before locking in your own picks.

So who wins Florida State vs. Penn? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks... If you're already a member, see the picks below!