No. 4 Florida State cannot afford a loss to No. 14 Louisville in the ACC Championship game on Saturday night. The Seminoles completed an undefeated regular season with a win over Florida last week, but a loss in this game would likely knock them out of the College Football Playoff picture. Louisville suffered its second loss of the season last week, falling to Kentucky by a touchdown in a rivalry game. FSU has uncertainty at quarterback with Jordan Travis (leg) out and backup Tate Rodemaker considered a game-day decision (head).

The Seminoles are 1-point favorites in the latest Florida State vs. Louisville odds via SportsLine consensus, while the over/under for total points scored is 46.5. Florida State is a -119 (risk $119 to win $100) favorite on the money line, with Louisville listed as a +101 underdog (see up-to-date odds for every game this week on our college football odds page). 

Before you make any ACC Championship picks or any other college football predictions, you NEED to see which side proven SportsLine expert Jimmie Kaylor is on. 

Kaylor is a NFL, college football, and DFS expert for SportsLine, who has covered the NFL and college football for close to a decade as a member of the Pro Football Writers of America. His background as a former college football All-American and NFL player gives him a unique perspective when building his fantasy lineups and locking in his betting picks. He has his finger on the pulse of the college football landscape and has been cashing in big for the last two years. 

Kaylor has been red-hot all season, going 73-28-2 overall on his college football best bets for SportsLine this season so far. He is up over 46.05 units, returning a profit of $4,605 for $100 bettors. Anyone who has followed his picks this season is way up.

Now, Kaylor has locked in a confident against-the-spread pick for Florida State vs. Louisville in the ACC Championship. We can tell you he's leaning Over on the point total, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Florida State vs. Louisville in the ACC Championship on Saturday, and what critical X-factor makes one side of the spread a must-back? ... Join SportsLine right now to see which side of the spread to jump on, all from the expert who is on a 73-28 roll betting on college football this season, and find out!