The Arizona Diamondbacks and St. Louis Cardinals meet in the third and deciding game of their series on Wednesday. St. Louis won the opener 5-3, while Arizona cruised to a 14-1 win in Tuesday's game. The Diamondbacks (12-13), who are third in the National League West, have won three of the five meetings with St. Louis this season. The Cardinals (10-14), who are fifth in the NL Central, have dropped five of six.

First pitch is set for 1:15 p.m. ET from Busch Stadium in St. Louis. The Cardinals are the -114 money-line favorites (risk $114 to win $100) in the latest Diamondbacks vs. Cardinals odds, while Arizona is a -105 underdog. The over/under for total runs scored is 8. Before you make any Diamondbacks vs. Cardinals picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 5 of the 2024 MLB season on a profitable 110-85 run on top-rated MLB picks dating back to last season, and it has excelled on top-rated run-line picks during that span, going 19-7 (+737). Anybody following it has seen big returns.

The model knows Arizona second baseman Ketel Marte has been red hot over the past 10 games. In a 12-11 win over the Chicago Cubs on April 16, he was 4-for-6 with a homer and RBI. In a 5-3 loss to the Cubs on April 17, he was 3-for-4 with a double, home run and two RBI. He had a four-hit performance with a double and RBI in Friday's win at San Francisco. For the season, he is batting .324 with eight doubles, five homers, 14 RBI and 23 runs scored.

The model also knows Cardinals shortstop Masyn Winn is off to a fast start to the season. In 22 games, he is batting .313 with three doubles, two triples, six RBI and eight runs scored. He has hits in six of his past 10 games, including a 2-for-3 performance with a double and a walk in a 3-1 win at Oakland on April 15. He was 2-for-4 with a triple, RBI and two runs scored in a 9-6 win at Arizona on April 12.

For Wednesday, the model has set its sights on Diamondbacks vs. Cardinals. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value! You ABSOLUTELY need to see the model before locking in any MLB picks.

Who wins Diamondbacks vs. Cardinals, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side you should be all over, all from the model that's 110-85 on top-rated MLB picks!