The 17th-ranked UConn Huskies look for their sixth win in a row when they take on the Creighton Bluejays in a key Big East Conference matchup on Tuesday night. The Huskies (15-4, 6-2) are looking for their first-ever win over the Bluejays (12-7, 4-4). Creighton holds a 3-0 edge in the all-time series with all of the games played last season.

Tipoff from XL Center in Hartford, Conn., is set for 6:30 p.m. ET. UConn is favored by 10.5 points at Caesars Sportsbook, while the over-under for total points is set at 135 (see up-to-date odds for every game this week on our college basketball odds page).

Before making any Creighton vs. UConn picks, you NEED to check out the college basketball predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every Division I college basketball game 10,000 times. Over the past five-plus years, the proprietary computer model has generated an impressive profit of over $2,400 for $100 players on its top-rated college basketball picks against the spread. Anyone who has followed it has seen HUGE returns.

The model knows the Huskies have seven players averaging six points or more, led by senior guard R.J. Cole. Cole blistered the DePaul defense for 25 points on Saturday, the fifth time he has reached 20 points or more this season. He has scored in double figures in 16 games, including 14 of the last 15. In his collegiate career, which began at Howard, Cole has started 106 of 109 games played and is averaging 19.2 points in that span. This season, he is averaging 16.1 points, 4.6 assists, 3.7 rebounds and 1.4 steals per game and is an 89.3 percent free-throw shooter.

The model also knows the Bluejays have four players averaging double figures, led by fifth-year senior guard Alex O'Connell, who played his first three seasons at Duke. O'Connell averages 12.8 points, 5.3 rebounds and 1.7 assists per game. He is also connecting on 47.6 percent of his field goals, including 37.9 percent from 3-point range, and 88.9 percent from the free-throw line. O'Connell had seven or more points in just three of 24 games last season, but has done it in all but two games this year. He had a career-high 28 points, including 6 of 9 3-pointers in the win over St. John's on Jan. 19.

Now, it has set its sights on Creighton vs. UConn. It is leaning Over on the total and it also says one side of the spread hits 60 percent of the time! You ABSOLUTELY need to see it before locking in any college basketball picks.

Who wins Creighton vs. UConn? And which side of the spread hits 60 percent of the time? ... Join SportsLine right now to find out which side of the Creighton vs. UConn spread you should be all over Tuesday, all from the model on a roll on college basketball picks!