The Washington Commanders open their 2022 NFL season hosting the Jacksonville Jaguars at 1 p.m. ET on Sunday at FedEx Field. The Commanders will be guided by Carson Wentz, who was acquired via trade this offseason. The Jaguars will be looking for a big step forward from 2021 No. 1 overall pick Trevor Lawrence in his second NFL season. Wahington ended last year third in the NFC East, while Jacksonville finished fourth in the AFC South. 

Washington is favored by 3 points in the latest Commanders vs. Jaguars odds from Caesars Sportsbook, and the over/under is set at 44. Before you make any Jaguars vs. Commanders picks and predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up over $7,500 for $100 players on top-rated NFL picks since its inception. The model enters the 2022 NFL season on an incredible 138-97 run on top-rated NFL picks that dates back to the 2017 season. Amazingly, it hasn't missed a top-rated pick since Week 15 last season. The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

Now, it has simulated Commanders vs. Jaguars 10,000 times and the results are in. We can tell you that the model is leaning Under on the point total, and it also says one side of the spread has all the value. You absolutely need to see it before locking in your own picks.

So who wins Commanders vs. Jaguars? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.