The class of the AFC South will be on display when the Indianapolis Colts visit the Tennessee Titans on Thursday Night Football. Kickoff at Nissan Stadium is set for 8:20 p.m. ET. The game is a pick'em in the latest Colts vs. Titans odds from William Hill Sportsbook, while the over-under is 48.5.

Before you make any Colts vs. Titans picks or any other NFL predictions, you NEED to see which side SportsLine expert R.J. White is on. 

CBS Sports' NFL editor, White enters Week 10 on a sizzling 31-21 run. It's no surprise, as White twice has cashed huge in the world's most prestigious football handicapping competition -- the Las Vegas SuperContest.

White has a particularly keen eye for the Colts. In fact, he is an impressive 28-15 in his last 43 against the spread picks involving the Colts! Anyone who has followed him is WAY UP.

Now, White has locked in another confident against the spread pick for Colts vs. Titans. We can tell you he's leaning Under, but he knows a crucial X-factor makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own.

Who wins Colts vs. Titans on Thursday Night Football? And which crucial X-factor makes one side of the spread hit HARD? ... Join SportsLine right now to see which side of the Colts vs. Titans spread to jump on, all from the expert who's an outstanding 28-15 on Colts picks!