The Week 6 college football schedule features hitting the road for difficult contests. No. 4 Tennessee is a 14-point favorite at Arkansas in the Week 6 college football odds, while No. 9 Missouri is a 2.5-point underdog at Texas A&M. Elsewhere, No. 1 Alabama is a 23.5-point favorite at Vanderbilt, and No. 10 Michigan is a 1.5-point underdog at Washington. The Wolverines are 11-0 in their last 11 games on the road, while the Huskies have won 17 consecutive games at home. 

Before making any college football picks for those games or others in Week 6, be sure to see what the SportsLine Projection Model has to say. 

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college spread football picks. It also went a sizzling 6-0 on all top-rated college football picks in Week 5. Anyone who has followed it has seen STRONG returns! Anyone who has followed it has seen STRONG returns!

Now, it has studied the latest college football odds (see the latest college football lines for each matchup this week on our college football odds page), simulated every single play for every Week 6 game, and the results are in. 

One of the college picks the model is high on during Week 6: Iowa (+18.5) stays within the big spread at No. 3 Ohio State in a 3:30 p.m. ET matchup (CBS) on Saturday, with the Hawkeyes covering in well over 50% of simulations.

Another prediction: California (+10) plays a one-score game against No. 8 Miami in a 10:30 p.m. ET kickoff on Saturday. The model has the Golden Bears covering nearly 60% of the time.  

The model has also made the call on who wins and covers in every other FBS matchup, and it's calling for seven underdogs to win outright!

So which college football teams should you back in Week 6, and which underdogs win outright? ... Join SportsLine now to see who wins and covers every single game, all from the model that has returned well over $2,000 in profit on top-rated ATS picks since its inception! ... You've unlocked our best deal! Get your first month of SportsLine for ONLY $1 with the promo code "LEAGUE"! Join here!