No. 24 Boston College has been one of the feel-good stories during the early portion of the 2024 college football season and new head coach Bill O'Brien will face his biggest test yet on Saturday when the Eagles travel to take on the No. 6 Missouri Tigers. Missouri is favored by 14.5 according to the latest Week 3 college football odds via the SportsLine consensus and that is the only ranked matchup on Saturday, but there will be plenty of conference games and rivalries.

The notable Week 3 matchups on Saturday include Alabama vs. Wisconsin, Oregon vs. Oregon State, Georgia vs. Kentucky and Colorado vs. Colorado State. Before you make any Week 3 college football predictions, be sure to checkout the Week 3 college football picks from our proven CFB expert Thomas Casale.

A frequent guest on national radio and TV shows to discuss college sports, Casale has been betting -- and winning -- for more than 30 years. 

Over the past two college football seasons, Casale is 122-92-5 (57%) overall and 26-8 (76.4%) in bowl games -- all publicly documented. Just last week, Casale advised SportsLine members to back Nebraska (-27.5) against UTEP. The Cornhuskers easily covered in a 40-7 win over UTEP.

Now, he's turned his attention to the 2024 Week 3 college football odds (see the latest college football lines for each game this week on our college football odds page) and is revealing his two top plays. 

We can tell you Casale is backing Alabama (-16.5) against Wisconsin on Saturday. "Alabama has been dealing with offensive line injuries but starting LT Kadyn Proctor should return this week," Casale said. "It is also important to note that over 80% of the Tide's offensive production vs. South Florida came after Elijah Pritchett replaced Wilkin Formby (4 holding penalties) at right tackle. Pritchett had been sitting out with a minor injury but came off the bench late in the game. With the offensive line trending up, look for Alabama's running game to dominate." 

Casale has also found two other college football picks he loves, including backing an underdog against the spread in a major rivalry game. You ABSOLUTELY need to see what he's playing before locking in any college football picks.

What are Casale's best bets for Week 3 in the 2024 college football season, and which lines should you jump on now? ... Join SportsLine right now to see Thomas Casale's best bets, all from one of the top college football analysts in the nation!