The No. 24 Clemson Tigers will face off against the South Carolina Gamecocks in a rivalry meeting between undefeated teams on Wednesday night. Tipoff is set for 8 p.m. ET at Littlejohn Coliseum. Clemson is favored by 8.5 points in the latest Clemson vs. South Carolina odds, while the over/under is set at 139.5 points, per SportsLine consensus. 

Before entering any South Carolina vs. Clemson picks, you NEED to see the NCAA Basketball predictions from the model at SportsLine.

The model simulates every Division I college basketball game 10,000 times. It enters Week 5 of the 2023-24 season on a 98-61 roll on all top-rated college basketball picks dating back to last season, returning more than $2,000 for $100 players. It is also off to a 10-2 start on top-rated spread picks this season. Anyone following has seen HUGE returns.

The model has simulated Clemson vs. South Carolina 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60% of simulations. You can only see the pick at SportsLine.

So who wins Clemson vs. South Carolina? And which side of the spread hits well over 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college basketball picks. If you're already a member, see the picks below!