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    Cincinnati vs. Notre Dame odds, line, spread: Proven model reveals college football picks, predictions for Week 5, 2021

    The SportsLine projection model has a pick for the clash between No. 7 Cincinnati and No. 9 Notre Dame

    A pair of top-10 foes meet when the No. 7 Cincinnati Bearcats face the No. 9 Notre Dame Fighting Irish in a key nonconference battle on Saturday. Kickoff from Notre Dame Stadium in South Bend, Ind., is set for 2:30 p.m. ET. The Bearcats have started the season 3-0, while the Fighting Irish are 4-0.

    The Bearcats are led by senior quarterback Desmond Ridder, the 2020 AAC Player of the Year. Ridder has completed 54 of 83 passes (65.1 percent) for 748 yards and seven touchdowns. He has been intercepted twice and has a rating of 163.8. He has also rushed 20 times for 72 yards (3.6 average) and two TDs.

    Much of the Fighting Irish's success this season has been due to the play of its defense. Sophomore linebacker JD Bertrand leads the unit with 42 tackles, including 28 solo, through Notre Dame's first four games. That ranks 11th nationally and is the most by an Irish player through the first four games of a season since Manti Te'o had 54 in the first four games of the 2010 season. Last week against Wisconsin, Bertrand registered eight tackles, including seven solo.    

    The Bearcats are favored by two points in the latest Cincinnati vs. Notre Dame odds from Caesars Sportsbook, and the over-under is set at 50. Before entering any Cincinnati vs. Notre Dame picks, you'll want to see the college football predictions from the model at SportsLine.

    The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. After going a sizzling 9-3 in Week 4, It also enters Week 5 of the 2021 season on an 81-61 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

    Now, it has simulated Cincinnati vs. Notre Dame 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread has all the value. You absolutely need to see it before locking in your own picks.

    So who wins Cincinnati vs. Notre Dame? And which side of the spread has all the value? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks. 

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    SportsLine Staff
    SportsLine Staff

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