The San Francisco 49ers and Kansas City Chiefs will reunite in the 2024 Super Bowl after playing in the Big Game four years ago. Super Bowl 58 takes place on Sunday on CBS and Paramount+. Kickoff from Allegiant Stadium in Las Vegas is at 6:30 p.m. ET. San Francisco is a 2-point favorite in the latest 49ers vs. Chiefs odds from the SportsLine Consensus, and the over/under for total points scored is 47.5. The 49ers are -127 money-line favorites, while the Chiefs are +107 underdogs. The Chiefs have won and covered five straight games, while the 49ers have failed to cover in three straight. Sunday's game will be televised on CBS and streamed live on Paramount+ with their MUST-HAVE Premium plan, which you can now try FREE for the first week.

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Before making any Chiefs vs. 49ers picks or any other NFL predictions, you NEED to see what SportsLine senior analyst Larry Hartstein has to say, given his mastery of picks in games involving Kansas City.

A former lead writer for Covers and The Linemakers, Hartstein combines a vast network of Vegas sources with an analytical approach he honed working for Pro Football Focus. He tied for 52nd place (out of 1,598 entries) in the 2022 Westgate Las Vegas SuperContest, going 53-34-3 ATS. Those selections form the basis of his weekly SportsLine NFL best bets, which are 195-147-2 over his last 344 picks (+1877).

Most importantly, Hartstein has a read on the pulse of the Chiefs. He is 32-21 (+855) on his last 53 against the spread picks in games involving Kansas City! Anyone who has followed him is way up.

Hartstein knows the Chiefs have elevated their play in the postseason, first with a double-digit home win over the Dolphins and then back-to-back road wins in Buffalo and Baltimore. Patrick Mahomes has been on quite a run in the postseason as he has 11 touchdowns versus zero interceptions over his last six playoff games. Kansas City has also experienced nothing but success against the 49ers in the Mahomes era, going 3-0 both straight-up and against-the-spread, winning all three by at least 11 points.

Hartstein also knows San Francisco is as complete a team as there is in the NFL as it ranks third in both scoring offense and scoring defense. The Niners have both the NFL leader in passer rating in QB Brock Purdy, as well as the league's rushing champion in RB Christian McCaffrey. San Francisco has also taken care of business as slim favorites, going 4-0 ATS when favored in between 1 and 3.5 points.

Now, Hartstein has locked in another confident against-the-spread pick for 49ers vs. Chiefs as he knows a crucial X-factor that makes one side of the spread a MUST-BACK! You ABSOLUTELY need to see what it is before locking in any picks of your own. And don't forget you can stream the game on Paramount+ on ANY DEVICE!

Who wins Chiefs vs. 49ers in Super Bowl 58, and which side of the spread hits HARD? ... Join SportsLine right now to find out which side of 49ers vs. Chiefs spread is a MUST-BACK, all from the expert on a 32-21 roll on picks involving Kansas City!