Charlotte is set to face off against FIU in a Conference USA matchup Friday on CBS Sports Network. The 49ers (3-2) are 1-0 are fresh off a loss to Illinois but are 1-0 in conference play. The Panthers (1-4) have yet to win a conference matchup. Charlotte is favored by 3.5 points in the latest odds from Caesars Sportsbook, while the Over-Under is set at 60.5 points. Kickoff is set for 7 p.m. ET.

Before making any Charlotte vs. FIU picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,300 for $100 players on its top-rated college football picks against the spread. It enters Week 6 of the 2021 season on a 12-4 run on all top-rated college football picks. Anyone who has followed it has seen HUGE returns.

The model knows that Charlotte's passing game has been strong this season. Grant DuBose has performed like a top-notch wideout. He's caught 24 passes for 393 yards and four scores through his first five games with the 49ers. 

The model also knows that FIU's balanced offense has produced at a high level. While the Panthers do have a losing record, Max Bortenschlager ranks 17th in passing yards with 1,368. Two of his receivers have more than 400 receiving yards on the year. D'Vonte Price has tallied 411 yards and six touchdowns on the ground for the Panthers on 76 attempts. 

Now, it has simulated Charlotte vs. FIU 10,000 times and the results are in. We can tell you that the model is leaning Over the total, and it's also generated a point-spread pick that hits in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks. 

So who wins Charlotte vs. FIU? And which side of the spread hits in almost 60 percent of simulations? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks.