Philadelphia 76ers (12-9) center Joel Embiid made his return to action after a four-game absence on Monday, and will be back on the floor Wednesday against the Cleveland Cavaliers (13-8). The Cavs could be in trouble around the basket with Embiid back in the mix, as center Jarrett Allen (back) and F/C Kevin Love (thumb) will both be out for the game. This is the first matchup between the two sides this season, but Philadelphia won all four meetings against Cleveland last year.

Game time from Rocket Mortgage Fieldhouse in Cleveland is set for 7 p.m. ET, where the Cavs are 8-1 this season. Cleveland is favored by 3.5 points in the latest Cavaliers vs. 76ers odds from Caesars Sportsbook, and the over/under is set at 210. Before you make any 76ers vs. Cavaliers picks and predictions, you HAVE to see what the SportsLine Projection Model is saying.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past four-plus seasons. The model enters Week 7 of the 2022-23 NBA season on a stunning 106-70 roll on all top-rated NBA picks that dates back to last season, returning more than $2,800! Anyone following it has seen HUGE returns!

Now, it has simulated Cavaliers vs. 76ers 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in well over 60 percent of simulations. You absolutely NEED to see it before locking in your own picks!

Who wins Cavaliers vs. 76ers? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NBA picks, and find out!