Kyler Murray and the Arizona Cardinals (2-3) will visit Geno Smith, DK Metcalf and the Seattle Seahawks (2-3) in an NFC West rivalry game at 4:05 p.m. ET on Sunday. Arizona has alternated losses and wins this season while Seattle won in Week 1 but has lost three of its last four. 

Arizona is favored by 2.5 points in the latest Cardinals vs. Seahawks odds from Caesars Sportsbook, and the over/under is set at 50.5 points. Before making any Seahawks vs. Cardinals picks or predictions, you'll want to see what the SportsLine Projection Model is saying.

The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 6 of the 2022 NFL season on an incredible 146-106 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP.

Now, it has simulated Cardinals vs. Seahawks 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits well over 50% of the time. You absolutely need to see it before locking in your own picks.

So who wins Seahawks vs. Cardinals? And which side of the spread hits well over 50% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.