The Arizona Cardinals host the Los Angeles Rams in an NFC West matchup on Sunday afternoon, with both teams looking to rebound after Week 1 road losses. Arizona lost 34-28 to Buffalo, though they had the ball deep in Bills territory late with a chance to take the lead. Los Angeles fell 26-20 in overtime to Detroit after a big comeback in regulation. The Rams have won 13 of the last 15 meetings, including both last season: 26-9 and 37-14.

Kickoff from State Farm Stadium is set for 4:05 p.m. ET. Arizona is a 1-point favorite in the latest Cardinals vs. Rams odds, while the over/under for total points is 48. The Cardinals are -110 money-line favorites (risk $110 to win $100). Before making any Los Angeles vs. Arizona picks, you NEED to check out the NFL predictions from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 2 of the 2024 NFL season on an incredible 184-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-22 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is WAY UP!

The model has simulated Cardinals vs. Rams 10,000 times and the results are in. We can tell you the model is leaning Over on the total. It also says one side of the spread cashes in over 50% of simulations! You ABSOLUTELY need to see what it is before locking in any NFL picks of your own!

Who wins Rams vs. Cardinals, and which side of the spread cashes in over 50% of simulations? Join SportsLine right now to find out which side of the spread you should be all over, all from the model that is up well over $7,000 on its NFL picks!