The St. Louis Cardinals (57-54) and the Chicago Cubs (54-59) match up in a Sunday Night Baseball contest. On Saturday, St. Louis defeated Chicago 5-4. Miles Mikolas (8-8, 4.99 ERA) is starting for the Cardinals. Justin Steele (2-5, 3.38 ERA) is on the mound for the Cubs. 

First pitch is scheduled for 7:10 p.m. ET from Wrigley Field in Chicago. The Cubs are the -148 money-line favorites (risk $148 to win $100) in the latest Cardinals vs. Cubs odds, while St. Louis is a +125 underdog. The over/under for total runs scored is 8.5 in the latest MLB odds via SportsLine consensus. 

Before making any Cardinals vs. Cubs picks or MLB predictions, you need to see what the SportsLine Projection Model has to say.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 19 of the 2024 MLB season 55-48 on all-top rated MLB picks this season. Dating back to last season, it is on a 24-11 roll on top-rated run-line picks (+877). Anybody following has seen STRONG returns!

The model knows St. Louis third baseman Nolan Arenado is a two-way playmaker. He has an accurate and powerful throwing arm. Offensively, he has great plate coverage. He's hitting .266 with 11 home runs and 48 RBI. 

The model also knows Chicago center fielder Cody Bellinger provides his team with a nice playmaker. Bellinger uses his power to spray the ball around, hitting .276 with 11 dingers and 42 RBI. On Thursday, he was 2-of-4 with a solo home run.

The model has simulated Cardinals vs. Cubs 10,000 times and the results are in. We can tell you the model is leaning Over on the run total, and it also says one side of the money line has ALL the value!

Who wins Cardinals vs. Cubs, and which side of the money line has ALL the value? ... Join SportsLine right now to find out which side of the money line you should be all over, all from the model on a 24-11 roll on top-rated MLB picks!