A Big 12 battle is on tap between the Baylor Bears and the No. 14 Iowa State Cyclones on Saturday, September 25 at McLane Stadium. Baylor is 3-0 overall and 1-0 at home, while Iowa State is 2-1 overall and 1-0 on the road. The Bears have yet to face a true test, while the Cyclones' lone loss came against No. 5 Iowa. 

Kickoff is at 3:30 p.m. ET. Iowa State is favored by 6.5 points in the latest Baylor vs. Iowa State odds from Caesars Sportsbook, and the over-under is set at 47.5. Before you make any Iowa State vs. Baylor picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. It also enters Week 4 of the 2021 season on a 72-58 run on all top-rated college football picks. Anyone who has followed it has seen HUGE returns.

Now, it has simulated Baylor vs. Iowa State 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread has all the value. You absolutely need to see it before locking in your own picks.

So who wins Baylor vs. Iowa State? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!