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Astros vs. Guardians odds, picks: Advanced computer MLB model releases selections for Sunday matchup

SportsLine's projection model generated selections for Sunday's matchup between the Houston Astros and the Cleveland Guardians

The Houston Astros and Cleveland Guardians meet for a matinee showdown at 12:05 p.m. ET on Sunday. Houston is listed as a -140 favorite (risk $140 to win $100) at Caesars Sportsbook, while the Over-Under is set at 8 (see up-to-date odds for every game this week on our MLB odds page). Before making any Astros vs. Guardians picks, you NEED to check out the MLB predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it enters Week 18 on a 20-14 roll on top-rated MLB picks, returning almost $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

The model knows the Astros are on a strong pace with a double-digit lead in the AL West. Houston has an excellent pitching staff, including Sunday's starter in Cristian Javier, and the Astros are also stout on offense. The Astros rank in the top three of the league in runs scored, home runs, slugging percentage, strikeout avoidance and more. Houston is also in the top five in total bases, doubles, and on-base percentage, illustrating overall offensive success.

The model also knows the Guardians lead the American League in strikeout avoidance on offense. In addition, Cleveland is a top-five team in hits, doubles, stolen bases, and batting average, and the Guardians are deploying a tremendous starting pitcher on Sunday. Triston McKenzie takes the ball for Cleveland with a 3.38 ERA and a 1.00 WHIP this season. He has a 2.04 ERA since the start of July and a 3.32 ERA in home starts in 2022.

Now, it has set its sights on Astros vs. Guardians. We can tell you the model is leaning Under the total, and it also says one team has all the value! You ABSOLUTELY need to see it before locking in any MLB picks.

Who wins Astros vs. Guardians? And which team has all the value on the money line? ... Join SportsLine right now to find out which side of the Astros vs. Guardians matchup you should be all over Sunday, all from the model on a roll on MLB picks!

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SportsLine Staff
SportsLine Staff

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