The No. 3 Ohio State Buckeyes welcome the Arkansas State Red Wolves to Columbus for a non-conference tilt at noon ET on Saturday. Ohio State is favored by 44.5 points at Caesars Sportsbook, while the over/under is set at 68.5 (see up-to-date odds for every game this week on our college football odds page). 

Before making any Arkansas State vs. Ohio State picks, you NEED to check out the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,500 for $100 players on its top-rated college football picks against the spread. It enters Week 2 of the 2022 college football season on a 48-37 run on all top-rated college football spread and money-line picks that dates back to 2021. Anyone who has followed it has seen huge returns.

The model knows Arkansas State struggled last season, but the Red Wolves played quite well in a blowout season-opening win. Arkansas State rushed for more than 300 yards and six touchdowns, and former Florida State quarterback James Blackman averaged more than 10 yards per attempt. The model also knows Ohio State is led by a Heisman frontrunner in quarterback C.J. Stroud, who is the reigning Big Ten Player of the Year. The Buckeyes also have a top-tier running game, and Ohio State held Notre Dame to 10 points in the opener, with a shutout in the second half. 

Now, it has set its sights on Arkansas State vs. Ohio State. We can tell you the model is leaning Over the total, and it also says one side of the spread hits in almost 60% of simulations! You ABSOLUTELY need to see it before locking in any college football picks.

Who wins Arkansas State vs. Ohio State? And which side of the spread hits in almost 60% of simulations? ... Join SportsLine right now to find out which side of the Arkansas State vs. Ohio State spread you should be all over Saturday, all from the model on a roll on college football picks!