The Arizona Wildcats will take on the BYU Cougars at 10:30 p.m. ET on Saturday at Allegiant Stadium. The Cougars are favored by 11.5 points in the latest Arizona vs. BYU odds from Caesars Sportsbook, and the over-under is set at 54. 

Before you make any BYU vs. Arizona picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past five-plus years, the proprietary computer model has generated a stunning profit of over $3,600 for $100 players on its top-rated college football picks against the spread. It also enters Week 1 of the 2021 season on a 57-37 run on all top-rated college football picks. Anyone who has followed it has seen huge returns.

Now, it has simulated Arizona vs. BYU 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in almost 80 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Arizona vs. BYU? And which side of the spread is a must-back? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!