The Las Vegas Raiders open a new era when they face the New Orleans Saints on Monday Night Football. Kickoff from Allegiant Stadium is set for 8:15 p.m. ET. New Orleans is a four-point favorite in the latest Saints vs. Raiders odds from William Hill, while the over-under is 48.5. Before you make any Saints vs. Raiders picks, you NEED to check out the latest NFL predictions from the SportsLine Projection Model. 

The model, which simulates every NFL game 10,000 times, is up over $7,400 for $100 players on its top-rated NFL picks since its inception five years ago. It went a perfect 4-0 on top-rated NFL picks in Week 1, including calling easy covers by the Ravens and Bills. The model enters Week 2 on an incredible 100-65 roll on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is WAY UP.

Now, it has set its sights on Saints vs. Raiders. We can tell you it's leaning Over, and it also says one side of the spread cashes in almost 60 percent of simulations! You ABSOLUTELY need to see it before locking in any NFL picks of your own.

So who wins Saints vs. Raiders on Monday? And which side of the spread hits in nearly 60 percent of simulations? ... Join SportsLine right now to find out which side of the Saints vs. Raiders spread you should be all over Monday, all from the advanced model that has returned over $7,400 on top-rated NFL picks!