The Virginia Cavaliers and the Duke Blue Devils will face off Saturday in an ACC clash at 4 p.m. ET at David A. Harrison III Field at Scott Stadium. Duke is 0-2 so far in 2020, while Virginia is playing its first game of the season. The Cavaliers are favored by 5.5 points in the latest Virginia vs. Duke odds from William Hill, and the Over-Under is set at 45.5. Before you make any Duke vs. Virginia picks, you'll want to see the college football predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $3,800 for $100 players on its top-rated college football picks against the spread. It is a sizzling 13-1 on top-rated picks through three weeks of the 2020 college football season, returning over $900 in profit already. Anyone who has followed it has seen huge returns.

Now, it has simulated Virginia vs. Duke 10,000 times and the results are in. We can tell you that the model is leaning Over, and it's also generated a point-spread pick that is hitting in 60 percent of simulations. You absolutely need to see it before locking in your own picks.

So who wins Virginia vs. Duke? And which side of the spread is hitting in 60 percent of simulations? ...Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks... If you're already a member, see the picks below!