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    Clemson vs. Boston College odds, line: 2021 college football picks, Week 5 predictions from proven model

    The SportsLine projection model has a pick for the clash between Boston College and Clemson.

    Saturday, the Clemson Tigers and the Boston College Eagles face off in their first ACC game of the season at 7:30 ET at Memorial Stadium. Clemson is looking for answers after losing two of its three FBS games this season, while Boston College is looking to start 5-0 for the first time since 2007.

    BC has had to make a switch at quarterback for the rest of the season, but has been holding opponents to less than 300 yards of offense in 2021. Clemson has had QB issues of its own, as D.J. Uiagalelei hasn't produced at Trevor Lawrence levels in his first full year as the starter. The Tigers are still favored by 14.5 points in the latest Clemson vs. Boston College odds from Caesars Sportsbook, and the over-under is set at 46. 

    Before entering any Boston College vs. Clemson picks, you'll want to see the college football predictions from the model at SportsLine.

    The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,100 for $100 players on its top-rated college football picks against the spread. It is a sizzling 25-13 on top-rated picks through seven weeks of the 2020 college football season, returning over $700 in profit already. Anyone who has followed it has seen huge returns.

    Now, it has simulated Clemson vs. Boston College 10,000 times and the results are in. We can tell you that the model is leaning Under, and it's also generated a point-spread pick that is hitting in almost 60 percent of simulations. You absolutely need to see it before locking in your own picks.

    So who wins Clemson vs. Boston College? And which side of the spread is hitting in over 50 percent of simulations? ... Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks ... If you're already a member, see the picks below!

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    SportsLine Staff
    SportsLine Staff

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