The Week 13 college football schedule is highlighted by a top-five Big Ten matchup as the second-ranked Ohio State Buckeyes will host the No. 5 Indiana Hoosiers. The Buckeyes are 13.5-point home favorites, per the Week 13 college football lines, and it's one of three ranked matchups of the week. Others include Army vs. Notre Dame (-14.5) and BYU vs. Arizona State (-3). Additionally, there are a couple of intriguing SEC contests in Ole Miss vs. Florida (+10) and Alabama vs. Oklahoma (+13.5). Which of these teams should warrant your Week 13 college football picks?

SportsLine's college football experts and advanced computer model have analyzed the entire Week 13 college football schedule and revealed the top college football picks, college football betting trends, college football best bets, and more. If you're not already a subscriber, join SportsLine here to get everything you need to crush your Week 13 college football picks!