Things are moving and shaking across the NFL. The week began with the New York Jets dismissing head coach Robert Saleh and demoting Nathaniel Hackett out of his play-calling duties. The San Francisco 49ers then began to get back on track with a 36-24 win over the Seattle Seahawks on Thursday Night Football. 

The remaining Week 6 schedule features a number of notable games. Rookie sensation Jayden Daniels will lead the Washington Commanders against Lamar Jackson and the Baltimore Ravens, the Detroit Lions and Dallas Cowboys will clash at Jerryworld, the suddenly high-flying Daniel Jones will try to lead the New York Giants to a win against a Cincinnati Bengals team that's desperate for a win, and the new-look Jets will contend with the Buffalo Bills.

Before you make your Week 6 NFL prop picks or bets, be sure you check out the top NFL picks and predictions from NFL props expert Alex Selesnick.

Selesnick (aka PropStarz) specializes in NFL, MLB and NBA prop betting, where he implements a combination of research, statistical analysis and mathematical modeling. 

The expert has been crushing his picks in all sports and entered the 2024 NFL season on a 461-350 streak, returning 62.6 units. The expert has also gone 206-142 on MLB prop plays for SportsLine this season and was 338-246 on NBA props last season.

After analyzing every matchup and hundreds of Week 6 NFL player props, one play PropStarz is backing is Chicago Bears WR DJ Moore Over 61.5 receiving yards against the Jaguars! PropStarz notes that Moore and QB Caleb Williams are coming off a strong effort, and should be able to keep it going against the Jacksonville defense. 

PropStarz has locked in several of his favorite Week 6 NFL prop picks, and they include a star running back turning in a big effort! You NEED to see the expert's best bets and the players you need to back (or fade) before deciding on your NFL Week 6 prop picks

Which NFL prop bets should you target in NFL Week 6? And which RB is a MUST-BACK? ... Join SportsLine right now to see the top NFL prop picks you can make, all from the expert who entered the season on a 461-350 run!