Crippling injuries to the game's top playmakers dominate the NFL headlines as we enter Week 5 of the 2024 NFL season. Stars such as Giants rookie WR Malik Nabers, Commanders RB Brian Robinson, Colts RB Jonathan Taylor and Chiefs WR Rashee Rice have joined a growing list of stars who are out because of injuries for an undetermined time.

Even so, the games go on and these unfortunate injuries pave the way for other players to step up and provide advantageous opportunities in both fantasy football and in the prop-betting market. What's more, the marquee matchup sees former Bills WR Stefon Diggs facing his former team as part of the Houston Texans. 

Before you make your Week 5 NFL prop picks or bets, be sure you check out the top NFL picks and predictions from NFL props expert Alex Selesnick.

Selesnick (aka PropStarz) specializes in NFL, MLB and NBA prop betting, where he implements a combination of research, statistical analysis and mathematical modeling. 

The expert has been crushing his picks in all sports and entered the 2024 NFL season on a 461-350 streak, returning 62.6 units. The expert has also gone 206-142 on MLB prop plays for SportsLine this season and was 338-246 on NBA props last season.

After analyzing every matchup and hundreds of Week 5 NFL player props, one play PropStarz is backing is Bills RB James Cook Over 57.5 rushing yards against the Texans! PropStarz notes that Houston ranks near the bottom of the league in most rushing defense categories, paving the way for the speedy, versatile back to have a huge performance. 

PropStarz has locked in several of his favorite Week 5 NFL prop picks, and they include a rookie running back falling short of his projected total yards! You NEED to see the expert's best bets and the players you need to back (or fade) before deciding on your NFL Week 5 prop picks

Which NFL prop bets should you target in NFL Week 5? And which quarterback is a MUST-BACK? ... Join SportsLine right now to see the top NFL prop picks you can make, all from the expert who entered the season on a 461-350 run!