A spot in the semifinals is on the line when defending champion Manchester City host Real Madrid in the second leg of their quarterfinal tie in the 2023-24 UEFA Champions League on Wednesday. Manchester City, who defeated Real Madrid in the semis last year en route to their first Champions League title, had their 10-game winning streak in the competition halted when they played to a 3-3 draw against Los Blancos in the first leg last Tuesday. Seeking their record 15th crown, Real Madrid won their first seven UCL matches before settling for back-to-back draws.

Kickoff at Etihad Stadium is set for 3 p.m. ET. The Citizens are -180 favorites (risk $180 to win $100) in the latest Manchester City vs. Real Madrid odds, while Los Blancos are +440 underdogs. A 90-minute draw is priced at +360 and the over/under for total goals scored is 3.5 (For more soccer coverage, click here).

Before you lock in your Real Madrid vs. Manchester City picks or UEFA Champions League predictions, you NEED to see what SportsLine's soccer expert Martin Green has to say.

After working in the sports betting industry for several years, Green became a professional sports writer and handicapper and has covered the game worldwide. Last year, Green was profitable in multiple areas on his soccer picks, including the Champions League (+3.05 units), FA Cup (+3.07), EFL Cup (+4.47) and Euro 2024 qualifiers (+6.30), among others. 

He also has been solid with his Premier League picks this year, going 21-14 (+6.92).

Green knows Manchester City enter Wednesday with a 27-game unbeaten streak across all competitions (22-5-0) and have been even better at home, where they have gone 41 consecutive matches without a loss. The Citizens also have been enjoying a lengthy run of success in the Champions League, going without a defeat in the competition over their last 22 contests. Man City have three players in the top 10 of the UCL in goals, as Norwegian striker Erling Haaland is tied for second with six while Argentinian forward Julian Alvarez and midfielder Phil Foden have scored five apiece to share fifth place with three others.

The expert also is aware that Real Madrid also haven't been beaten in a while, recording 10 wins and five draws over their last 15 matches across all competitions. Brazilian winger Rodrygo scored his fourth goal of the competition in the first leg to pull even with midfielder Jude Bellingham for the team lead, and Uruguayan midfielder Federico Valverde converted in the 79th minute to knot the match. Los Blancos also have some skilled set-up men as Bellingham and Brazilian winger Vinicius Junior are tied with four others for the UCL lead with four assists each.

Green has taken an in-depth look at the Manchester City vs. Real Madrid showdown and is leaning Over on the total. He also has locked in three CONFIDENT best bets and is offering a full breakdown of this UEFA Champions League matchup! You ABSOLUTELY need to see his picks and analysis before making any selections of your own.

Who wins Manchester City vs. Real Madrid on Wednesday, and what are the best bets you can make? ... Join SportsLine now to see Martin Green's picks for Real Madrid vs. Manchester City, all from the expert who has been profitable in multiple areas on his soccer picks!