Serena Williams hopes to extend her career a bit longer when she meets Ajla Tomljanovic in the third round of the 2022 U.S. Open at Arthur Ashe Stadium in Flushing Meadows on Friday at 7 p.m. ET. The 40-year-old superstar, who is expected to retire after the tournament, posted a 7-6 (7-4), 2-6, 6-2 victory over No. 2 seed Anett Kontaveit in the second round to keep her hopes of a record-tying 24th Grand Slam title alive. Williams, who is one behind Margaret Court on the all-time list, has won the U.S. Open on six occasions - most recently in 2014, the last of a three-year run.

Williams is a -160 favorite (risk $160 to win $100) in the latest Williams vs. Tomljanovic odds from Caesars Sportsbook, while Tomljanovic is a +125 underdog. The over/under for total games in the match is 21.5, with Williams favored by 2.5 games. Before you make any Tomljanovic vs. Williams picks or 2022 U.S. Open predictions, you need to see what tennis expert Jose Onorato has to say.

Onorato grew up playing competitive tennis in Caracas, Venezuela. After coming to the U.S., he trained with famed coach Nick Bollettieri at IMG Academy in Florida and faced players like Robert Farah, now one of the world's top-ranked doubles players.

Onorato, who holds dual degrees in finance and economics from the University of Miami, does extensive research before placing any tennis bet. He studies current form, players' tendencies on a particular surface, weather conditions and many other relevant factors. That systematic approach helped Onorato go 69-46 -- up 54.98 units -- from January through July.

Now, Onorato has scrutinized the Williams vs. Tomljanovic matchup in the third round of the 2022 U.S. Open and released his coveted pick. You ABSOLUTELY need to see what it is before locking in any 2022 U.S. Open picks of your own!

Who wins the Williams vs. Tomljanovic match in the third round of the 2022 U.S. Open? ... Join SportsLine right now to see Jose Onorato's prediction and analysis for the 2022 U.S. Open women's match, all from the tennis expert who went 69-46 from January through July!